SCHEMBL32665071

SCHEMBL32665071

O=C(O)c1cc(C(=O)O)c2cc3c(C(=O)O)cc(C(=O)O)cc3cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.46
BCL2L1 Q07817 1/20 0.44
TSHR P16473 2/20 0.43
ALOX15 P16050 1/20 0.43
HIF1A Q16665 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
TPMT P51580 3/20 0.39
KDM4E B2RXH2 2/20 0.39
TP53 P04637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231134 0.89 PTPN1 (0.44) PTPN1BCL2L1TSHRALOX15HIF1A
SCHEMBL8714081 0.88 PTPN1 (0.41) PTPN1BCL2L1TSHRALOX15HIF1A
SCHEMBL1355689 0.86 PTPN1 (0.51) PTPN1HIF1AMEN1KMT2AKDM4E
SCHEMBL29904700 0.83 PTPN1 (0.67) PTPN1BCL2L1TSHRMEN1KMT2A
SCHEMBL121791 0.83 PTPN1 (0.67) PTPN1BCL2L1TSHRMEN1KMT2A
SCHEMBL29385806 0.83 PTPN1 (0.67) PTPN1BCL2L1TSHRMEN1KMT2A
SCHEMBL1879909 0.81 PTPN1 (0.59) PTPN1TSHRMEN1KMT2ACA12
SCHEMBL29904704 0.81 PTPN1 (0.59) PTPN1TSHRMEN1KMT2ACA12
SCHEMBL31401727 0.81 PTPN1 (0.59) PTPN1TSHRMEN1KMT2ACA12
SCHEMBL29659433 0.80 CA12 (0.48) PTPN1TSHRALOX15HIF1ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE CONWAY DAVID JONATHAN (US) 2026-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022138-A1 METAL ORGANIC FRAMEWORKS FOR OLED APPLICATIONS AND METHODS OF USE TRPV3, VDR, TRPC3 PTPN1 2723/4885BCL2L1 514/4885TSHR 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.