Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666652 | 0.87 | KCNH2 (0.53) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL6583019 | 0.84 | MAOB (0.56) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL32665380 | 0.84 | KDM1A (0.52) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL6583023 | 0.82 | SPHK1 (0.58) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL6588487 | 0.82 | SPHK1 (0.55) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL12354455 | 0.81 | SPHK1 (0.60) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL28190298 | 0.81 | TNKS2 (0.52) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL23364801 | 0.80 | KCNH2 (0.49) | KDM1ACYP4F2CYP4A11KCNH2MAOB | |
| SCHEMBL9162340 | 0.80 | ALOX5 (0.48) | KDM1AKCNH2MAOBALOX5MEN1 | |
| SCHEMBL9162330 | 0.80 | ALOX5 (0.48) | KDM1AKCNH2MAOBALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KDM1A 4345/4885CYP4F2 2351/4885CYP4A11 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.