Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476968 | 0.86 | MTNR1A (0.48) | KDM4ASERPINE1MTNR1AMTNR1B | |
| SCHEMBL2002789 | 0.84 | KDM4A (0.41) | KDM4ASERPINE1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL25574990 | 0.84 | AAK1 (0.49) | KDM4ACACNA1HCACNA1BCACNA1CCA12 | |
| SCHEMBL22482387 | 0.82 | KDM4A (0.44) | KDM4ASERPINE1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL29675308 | 0.82 | KDM4A (0.44) | KDM4ASERPINE1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL2004184 | 0.82 | BRD9 (0.41) | KDM4ACACNA1HCACNA1BCACNA1CCA12 | |
| SCHEMBL4894133 | 0.81 | NQO2 (0.49) | KDM4ANQO2KCNA5EPHX2NR1H4 | |
| SCHEMBL24885830 | 0.81 | NQO2 (0.49) | KDM4ANQO2KCNA5CTSSCTSK | |
| SCHEMBL29467997 | 0.81 | KDM4A (0.41) | KDM4ASERPINE1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL3154474 | 0.81 | TRPA1 (0.46) | KDM4ACACNA1HCACNA1BCACNA1CKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KDM4A 4180/4885SERPINE1 3684/4885CACNA1H 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.