Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 5/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665515 | 0.85 | MGLL (0.46) | PTGS1PTGS2ELANEMGLLGSK3A | |
| SCHEMBL32665046 | 0.78 | PTGS1 (0.46) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL29585298 | 0.77 | PTGS1 (0.61) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL7218634 | 0.77 | PTGS1 (0.61) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL32665049 | 0.76 | PTGS1 (0.37) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL2785687 | 0.75 | PTGS1 (0.73) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL28967206 | 0.74 | ELANE (0.55) | ELANEMGLLHSD17B10KDM4ETSHR | |
| SCHEMBL32665464 | 0.72 | MGLL (0.47) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL32665530 | 0.72 | MGLL (0.47) | PTGS1PTGS2MGLLGSK3AGSK3B | |
| SCHEMBL28145883 | 0.72 | CYP2A13 (0.55) | HSD17B10KDM4ETP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | PTGS1 3292/4885PTGS2 3278/4885ELANE 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.