SCHEMBL7218634

SCHEMBL7218634

COc1ccccc1CN1C(=O)C=CC1=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.61
PTGS2 P35354 1/20 0.61
USP2 O75604 1/20 0.59
HSD17B10 Q99714 1/20 0.59
GAA P10253 3/20 0.57
KDM4E B2RXH2 1/20 0.57
RECQL P46063 1/20 0.57
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
MGLL Q99685 2/20 0.51
GSK3A P49840 2/20 0.50
GSK3B P49841 2/20 0.50
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.47
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29585298 1.00 PTGS1 (0.61) PTGS1PTGS2USP2HSD17B10GAA
SCHEMBL826239 0.85 PTGS1 (0.51) PTGS1PTGS2GAAKDM4ERECQL
SCHEMBL18669183 0.81 GAA (0.78) USP2HSD17B10GAAKDM4ERECQL
SCHEMBL2785687 0.80 PTGS1 (0.73) PTGS1PTGS2RECQLMGLLGSK3A
SCHEMBL3422052 0.78 USP2 (0.58) USP2HSD17B10GAAKDM4ERECQL
SCHEMBL13486597 0.78 GSK3A (0.58) GAAKDM4EMEN1KMT2ATSHR
SCHEMBL4597149 0.78 TGM2 (0.61) USP2HSD17B10GAAKDM4ERECQL
SCHEMBL10341830 0.77 USP2 (0.57) USP2HSD17B10GAAKDM4ERECQL
SCHEMBL32665162 0.77 PTGS1 (0.54) PTGS1PTGS2USP2HSD17B10GAA
SCHEMBL720414 0.76 PTGS1 (1.00) PTGS1PTGS2MEN1KMT2AMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113136239-B Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2022-05-13 CN disclosed
CN-113563152-A Method for treating C five fraction and use of olefinic bond-containing compound 清华大学 2021-10-29 CN disclosed
CN-113136239-A Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2021-07-20 CN disclosed
CN-113122315-A Method for treating ethylene tar and use of carbonyl compound containing olefinic bond 清华大学 2021-07-16 CN disclosed
CN-113024724-A Method for continuous polymerization of cracked fractions 清华大学 2021-06-25 CN disclosed
CN-112852482-A Method for treating cracked fractions and use of compounds containing olefinic bonds 清华大学 2021-05-28 CN disclosed
US-20140049728-A1 LIGHT GUIDE PLATE, LIGHT-EMITTING UNIT AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME CHI MEI CORPORATION (TW) 2014-02-20 US disclosed
US-6627364-B2 Contains (A) a colorant, (B) a binder resin and (C) a solvent having a boiling point of 245 degrees C. or more at normal pressure. SEIKO EPSON CORPORATION (JP) 2003-09-30 US disclosed
US-20020128351-A1 Ink jet color filter resin composition, color filter and color filter production process SEIKO EPSON CORPORATION (JP) 2002-09-12 US disclosed
EP-1048700-A1 Ink jet color filter resin composition, color filter production process SEIKO EPSON CORPORATION (JP) 2000-11-02 EP disclosed