Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665168 | 0.97 | DRD2 (0.44) | LMNAGAAMAPTDRD2DRD4 | |
| SCHEMBL32665109 | 0.93 | CYP2C9 (0.44) | LMNAMAPTDRD2DRD4SMN1; SMN2 | |
| SCHEMBL32665531 | 0.88 | GAA (0.43) | LMNAGAAMAPTDRD2DRD4 | |
| SCHEMBL32665598 | 0.86 | NPC1 (0.46) | LMNAGAAMAPTDRD2KMT2A | |
| SCHEMBL32665453 | 0.83 | NPC1 (0.48) | DRD2KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL32665129 | 0.79 | GLA (0.43) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29444954 | 0.76 | NPC1 (0.55) | LMNAGAANAMPTSMN1; SMN2NPC1 | |
| SCHEMBL32665571 | 0.76 | F10 (0.48) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL32665323 | 0.75 | F10 (0.47) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL32665073 | 0.74 | CA2 (0.43) | SMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | LMNA 2336/4885GAA 4545/4885MAPT 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.