Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665614 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BCKS1BSKP1SKP2 | |
| SCHEMBL3893845 | 0.94 | KMT2A (0.48) | MTNR1AMTNR1BKMT2AL3MBTL1BTK | |
| SCHEMBL32665202 | 0.94 | CKS1B (0.52) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL32665123 | 0.90 | ACACB (0.52) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL27451694 | 0.86 | CKS1B (0.53) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL8049478 | 0.84 | MTNR1A (0.66) | MTNR1AMTNR1BBTKPIM1PIM3 | |
| SCHEMBL23500781 | 0.84 | CKS1B (0.56) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL15222937 | 0.84 | CKS1B (0.56) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL32665560 | 0.84 | RET (0.44) | KMT2AL3MBTL1F10USP2MAPT | |
| SCHEMBL12321963 | 0.84 | CKS1B (0.53) | CKS1BSKP1SKP2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | MTNR1A 1595/4885MTNR1B 2143/4885CKS1B 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.