Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665166 | 0.84 | ELANE (0.52) | KMT2AELANELMNASMN1; SMN2KDM4E | |
| SCHEMBL32665556 | 0.80 | PTPN1 (0.41) | KMT2AELANEKAT6AMEN1POLB | |
| SCHEMBL7787275 | 0.79 | SMN1; SMN2 (0.51) | KMT2AKAT6ALMNASMN1; SMN2KDM4E | |
| SCHEMBL32665440 | 0.77 | KMT2A (0.45) | KMT2ASMN1; SMN2ALDH1A1MEN1POLB | |
| SCHEMBL29867597 | 0.75 | KMT2A (0.46) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12845255 | 0.75 | KCNK3 (0.49) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL26914818 | 0.75 | KMT2A (0.46) | KMT2ALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28509827 | 0.75 | KMT2A (0.46) | KMT2AKAT6ALMNASMN1; SMN2KDM4E | |
| SCHEMBL26664896 | 0.74 | ELANE (0.52) | ELANEKAT6ACES2BCHECES1 | |
| SCHEMBL19122203 | 0.72 | ELANE (0.53) | KMT2AELANELMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | KMT2A 4014/4885ELANE 1276/4885KAT6A 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.