Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665486 | 0.84 | KMT2A (0.45) | ELANELMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19122203 | 0.83 | ELANE (0.53) | ELANELMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL8577256 | 0.83 | LMNA (0.51) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4731724 | 0.83 | LMNA (0.51) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21034056 | 0.82 | L3MBTL1 (0.67) | ELANELMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27132922 | 0.81 | STS (0.51) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27029738 | 0.80 | STS (0.50) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27619652 | 0.78 | KMT2A (0.47) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11979662 | 0.77 | LMNA (0.50) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL32665331 | 0.77 | ELANE (0.47) | ELANEKDM4EALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ELANE 1276/4885LMNA 2336/4885KDM4E 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.