Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665519 | 0.82 | ELANE (0.48) | ELANE | |
| SCHEMBL17580831 | 0.78 | PTGS2 (0.42) | ELANEPTGS2FABP7FABP3FABP5 | |
| SCHEMBL5599136 | 0.78 | DRD2 (0.39) | ELANEPTGS2FABP7FABP3FABP5 | |
| SCHEMBL17600948 | 0.77 | PTGS2 (0.41) | ELANEPTGS2FABP7FABP3FABP5 | |
| SCHEMBL31444042 | 0.76 | ELANE (0.43) | ELANEALDH1A1HTR1AHTR7CA1 | |
| Iodide SCHEMBL29827459 | 0.76 | DRD2 (0.39) | ELANEPTGS2FABP7FABP3FABP5 | |
| SCHEMBL26664902 | 0.76 | ELANE (0.61) | ELANEALDH1A1HTR1ANFE2L2 | |
| SCHEMBL28479379 | 0.76 | ELANE (0.61) | ELANEPTGS2ALDH1A1NFE2L2 | |
| SCHEMBL31444250 | 0.74 | ELANE (0.59) | ELANEALDH1A1HTR7CA1CA2 | |
| SCHEMBL22475388 | 0.74 | ELANE (0.59) | ELANEALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ELANE 1276/4885PTGS2 3278/4885FABP7 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.