Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266361 | 0.85 | HTR2C (0.54) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL5585578 | 0.77 | ADRB2 (0.46) | SLC6A2SLC6A4HTR2CCCNT1CDK9 | |
| SCHEMBL3268109 | 0.75 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL3266841 | 0.74 | HTR2C (0.60) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL3267292 | 0.74 | HTR2C (0.54) | HTR2CHTR1AHTR6HTR2AHTR2B | |
| Acetic Acid SCHEMBL6184606 | 0.72 | HTR2C (0.44) | SLC6A2SLC6A4HTR2CHTR6HTR2A | |
| SCHEMBL15728433 | 0.72 | FGFR3 (0.51) | IL2MAP4K1KCNH2 | |
| SCHEMBL906145 | 0.72 | HTR2C (0.60) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL1714907 | 0.70 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL2873088 | 0.70 | HTR3E (0.68) | SLC6A2SLC6A4HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335907-B1 | PIPERAZINYLPYRAZINE COMPOUNDS AS AGONIST OR ANTAGONIST OF SEROTONIN 5HT-2 RECEPTOR | BIOVITRUM AB PUBL (SE) | 2010-06-09 | — | — | EP | claimed |