SCHEMBL32665746

SCHEMBL32665746

Cc1ccc(O)c(Nc2cc([N+](=O)[O-])ccn2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.57
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
KMT2A Q03164 9/20 0.49
MEN1 O00255 8/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 7/20 0.44
POLB P06746 3/20 0.44
NPC1 O15118 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
HTT P42858 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CRHBP P24387 2/20 0.43
CRHR2 Q13324 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32674563 0.82 MEN1 (0.52) GAAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL32665745 0.76 MEN1 (0.43) GAANCOA1NCOA3KMT2AMEN1
SCHEMBL13316448 0.76 ALDH1A1 (0.56) GAAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL16148749 0.75 KMT2A (0.62) GAANCOA1NCOA3KMT2AMEN1
SCHEMBL656281 0.74 MAPK8 (0.54) GAANCOA1NCOA3KMT2AMEN1
SCHEMBL2466036 0.72 MAPT (0.46) KMT2AMEN1SMN1; SMN2MAPTPOLB
SCHEMBL17010319 0.71 POLB (0.52) GAAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL17010318 0.71 POLB (0.52) GAAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL21281931 0.71 ROCK1 (0.57) GAAKMT2AMEN1MAPTNPC1
SCHEMBL25372501 0.70 ROCK1 (0.43) KMT2AMEN1MAPTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121405617-A 2- ((4-Aminopyridine-2-yl) amino) -4-methylphenol and synthetic method and application thereof 山东阳谷华泰化工股份有限公司 2026-01-27 CN disclosed