SCHEMBL32665745

SCHEMBL32665745

Cc1ccc(O)c(Nc2cc(N)ccn2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
GAA P10253 5/20 0.43
KARS1 Q15046 1/20 0.42
KDM4E B2RXH2 1/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CXCR2 P25025 1/20 0.40
NPC1 O15118 3/20 0.40
POLB P06746 2/20 0.40
KCNH2 Q12809 1/20 0.40
SCN5A Q14524 1/20 0.40
SCN9A Q15858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPKAPK2 P49137 1/20 0.39
MAPK10 P53779 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32674564 0.81 ESR1 (0.40) MEN1KMT2AGAAKARS1ALDH1A1
SCHEMBL32674561 0.80 MAPK10 (0.53) MEN1KMT2AGAACXCR2POLB
SCHEMBL32674593 0.76 KCNH2 (0.36) MEN1KMT2ANOS3NOS2KCNH2
SCHEMBL32665746 0.76 GAA (0.57) MEN1KMT2AGAAKDM4EALDH1A1
SCHEMBL20796356 0.73 KARS1 (0.45) MEN1KMT2AKARS1KDM4ENOS3
SCHEMBL13316450 0.72 KARS1 (0.50) MEN1KMT2AKARS1KDM4ENOS3
SCHEMBL28212946 0.72 TNNI3K (0.54) KMT2AKARS1KCNH2SCN5ASCN9A
SCHEMBL13316451 0.70 MAPK10 (0.53) MEN1KMT2AGAAKDM4ENOS3
SCHEMBL4665722 0.70 KCNH2 (0.64) KDM4EALDH1A1NPC1KCNH2SCN5A
SCHEMBL7936142 0.68 CXCR2 (0.58) MEN1KMT2AGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121405617-A 2- ((4-Aminopyridine-2-yl) amino) -4-methylphenol and synthetic method and application thereof 山东阳谷华泰化工股份有限公司 2026-01-27 CN disclosed
CN-121405617-A 2- ((4-Aminopyridine-2-yl) amino) -4-methylphenol and synthetic method and application thereof 山东阳谷华泰化工股份有限公司 2026-01-27 CN disclosed