Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylose SCHEMBL21468587 | 1.00 | HTT (0.49) | HTTHPGDKDM4EHSD17B10NPC1 | |
| Aspirin SCHEMBL2174051 | 0.84 | KDM4E (0.58) | HTTHPGDKDM4EHSD17B10CYP2C9 | |
| Aspirin SCHEMBL27691894 | 0.84 | KDM4E (0.58) | HTTHPGDKDM4EHSD17B10CYP2C9 | |
| Phthalic Acid SCHEMBL23567081 | 0.82 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1HMGB1NAPRT | |
| Phthalic Acid SCHEMBL30930043 | 0.82 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1HMGB1NAPRT | |
| Anthranilic Acid SCHEMBL27914571 | 0.80 | MAPT (0.41) | HPGDKDM4EHSD17B10NPC1RAB9A | |
| Alcohol SCHEMBL17255935 | 0.78 | HTT (0.70) | HTTHPGDKDM4EHSD17B10NPC1 | |
| Xylose SCHEMBL29915202 | 0.77 | ALDH1A1 (0.44) | HTTHPGDKDM4EHSD17B10NPC1 | |
| Demannose SCHEMBL25326591 | 0.77 | CLCN2 (0.40) | HTTKDM4ECYP2C9ALDH1A1TSHR | |
| Xylose SCHEMBL31303135 | 0.77 | TSHR (0.47) | HPGDKDM4EALDH1A1TSHRNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12537071-B1 | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins | BERMUDES DAVID GORDON (US) | 2026-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12537071-B1 | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins | ANTXR2, BCOR, ZFX | HTT 1769/4885HPGD 743/4885KDM4E 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.