SCHEMBL32666905

SCHEMBL32666905

C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cccc(C5(Cn6nccn6)CC(F)(F)C5)c4)c(=O)c3[nH]2)C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 13/20 0.37
▸ HSD17B10 Q99714 1/20 0.33
▸ CNR2 P34972 1/20 0.31
▸ BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27068273 0.92 BRD4 (0.32) BRD4
SCHEMBL32666859 0.89 CBLB (0.35) CBLBBRD4
SCHEMBL30999266 0.85 CBLB (0.51) CBLB
SCHEMBL27068279 0.84 CBLB (0.38) CBLBBRD4
SCHEMBL27068278 0.83 CBLB (0.35) CBLBHSD17B10BRD4
SCHEMBL27068276 0.83 CBLB (0.39) CBLBHSD17B10
SCHEMBL30728175 0.83 CBLB (0.39) CBLBHSD17B10
SCHEMBL27068275 0.82 BRD4 (0.32) BRD4
SCHEMBL27041435 0.82 CBLB (0.36) CBLBHSD17B10
SCHEMBL30728232 0.82 CBLB (0.48) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028336-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2026-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028336-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF CBLB, CBL, CBLC CBLB 1/4885HSD17B10 1224/4885CNR2 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback