Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667819 | 1.00 | KCNH2 (0.53) | KCNH2SLC2A1MAOB | |
| SCHEMBL27129890 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL27035907 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL27035903 | 0.86 | KCNH2 (0.64) | KCNH2SLC2A1 | |
| SCHEMBL32667729 | 0.84 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL27062102 | 0.84 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL32667775 | 0.82 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL27061392 | 0.82 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL27035905 | 0.81 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL27146010 | 0.81 | KCNH2 (0.62) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027101-A1 | BACTERIAL TOPOISOMERASE INHIBITORS | OHIO STATE INNOVATION FOUNDATION (US) | 2026-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027101-A1 | BACTERIAL TOPOISOMERASE INHIBITORS | TOP1, TOP2A, TOP2B | KCNH2 2730/4885SLC2A1 3530/4885MAOB 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.