SCHEMBL5669374

SCHEMBL5669374

CCCCC#Cc1c(C(=O)O)cccc1-c1cccc(C(=O)O)c1C#CCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
APEX1 P27695 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LTB4R2 Q9NPC1 6/20 0.41
TNK2 Q07912 1/20 0.41
TSHR P16473 1/20 0.41
PTPN11 Q06124 2/20 0.41
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
AGTR1 P30556 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669455 0.94 KDM4E (0.44) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL3266797 0.84 HTT (0.47) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL5667800 0.84 KDM4E (0.38) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL5667072 0.84 CXCR2 (0.39) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL5666941 0.80 KDM4E (0.50) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL19331451 0.79 KDM4E (0.56) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL5006713 0.79 KDM4E (0.49) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL2747203 0.78 CYP3A4 (0.51) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL3249278 0.76 APEX1 (0.46) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2
SCHEMBL5669429 0.76 KDM4E (0.43) KDM4ESMN1; SMN2HSD17B10LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed