Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24234909 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL5533465 | 0.91 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL28683268 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL28683299 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL17839852 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL29549443 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL3074569 | 0.79 | — | — | |
| SCHEMBL5830059 | 0.79 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL11127833 | 0.79 | ALDH1A1 (0.94) | ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4 | |
| SCHEMBL10271171 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | EVONIK OPERATIONS GMBH (DE) | 2026-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | INTS9, PUF60, INTS6 | ALDH1A1 2346/4885SMN1; SMN2 3892/4885TEAD1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.