SCHEMBL5533465

SCHEMBL5533465

O=C(CCl)NCCNC(=O)CCl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
SMN1; SMN2 Q16637 4/20 0.72
TEAD1 P28347 1/20 0.43
YAP1 P46937 1/20 0.43
TEAD4 Q15561 1/20 0.43
TEAD2 Q15562 1/20 0.43
TSHR P16473 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FAAH O00519 2/20 0.39
ECE1 P42892 1/20 0.35
NPC1 O15118 1/20 0.34
MITF O75030 1/20 0.34
XBP1 P17861 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
NOD2 Q9HC29 1/20 0.34
HTT P42858 1/20 0.34
MAPK1 P28482 1/20 0.34
PRMT1 Q99873 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24234909 0.91 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL32668010 0.91 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL17839852 0.88 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL11127833 0.87 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL3074569 0.87
SCHEMBL5830059 0.87 ALDH1A1 (0.83) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL5525368 0.86 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2TEAD1YAP1TEAD4
SCHEMBL11126451 0.84 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL8038216 0.84
SCHEMBL11097335 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules Belyntic GmbH (DE) 2025-11-18 US claimed
CN-114206902-B Method for modifying peptides immobilized on a solid support by means of a traceless reducing cleavable linker molecule 格瑞罗斯普罗泰恩科技公司 2025-02-21 CN claimed
US-20220363713-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES Belyntic GmbH (DE) 2022-11-17 US claimed
CN-114206902-A Method for modifying a peptide immobilized on a solid support by means of a traceless reductively cleavable linker molecule 贝兰迪克有限责任公司 2022-03-18 CN claimed
CN-114058173-A Process and composition for producing flexible polyurethane foams 赢创运营有限公司 2022-02-18 CN claimed
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules Belyntic GmbH (DE) 2025-11-18 US disclosed
CN-114206902-B Method for modifying peptides immobilized on a solid support by means of a traceless reducing cleavable linker molecule 格瑞罗斯普罗泰恩科技公司 2025-02-21 CN disclosed
EP-4010352-B1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES GYROS PROTEIN TECH AB (SE) 2023-10-18 EP disclosed
US-11788081-B2 Protein macrocyclization STICHTING VU (NL) 2023-10-17 US disclosed
US-20220363713-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES Belyntic GmbH (DE) 2022-11-17 US disclosed
EP-3883865-B1 SEAL OF A PORTION CAPSULE GCS GERMAN CAPSULE SOLUTION GMBH (DE) 2022-11-09 EP disclosed
EP-4010352-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES Belyntic GmbH (DE) 2022-06-15 EP disclosed
EP-1396514-A1 Anti-bacterial polymer and method for the preparation thereof, anti-bacterial polymer film and method for the preparation thereof, and article having such a film on the surface thereof ULVAC, INC. (JP) 2004-03-10 EP disclosed
WO-2003014192-A1 QUATERNARY POLYAMIDOAMINES, THE PRODUCTION THEREOF, CORRESPONDING AGENTS AND THE USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2003-02-20 WO disclosed
EP-1184377-A1 Hepatobiliary magnetic resonance contrast agents BRACCO International B.V. (NL) 2002-03-06 EP disclosed
WO-1995009161-A1 HEPATOBILIARY MAGNETIC RESONANCE CONTRAST AGENTS BRACCO INTERNATIONAL B.V. (NL) 1995-04-06 WO disclosed
US-5358704-A Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents BRISTOL-MYERS SQUIBB (US) 1994-10-25 US disclosed
US-4362528-A OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT SOCIETE ANONYME DITE: L'OREAL (FR) 1982-12-07 US disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed
US-4013787-A CATIONIC POLYMERS SOCIETE ANONYME DITE: L'OREAL (FR) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220363713-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES PTMS, VIP, HM13 ALDH1A1 1890/4885SMN1; SMN2 3665/4885TEAD1 2067/4885
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules PTMS, VIP, HM13 ALDH1A1 2067/4885SMN1; SMN2 3924/4885TEAD1 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.