SCHEMBL32669044

SCHEMBL32669044

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nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.53
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.38
HSD17B10 Q99714 1/20 0.33
CYP2D6 P10635 1/20 0.30
MAPK1 P28482 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3902385 1.00 TDP1 (0.53) TDP1CA1CA2CA7CA9
SCHEMBL3899157 1.00 TDP1 (0.53) TDP1CA1CA2CA7CA9
SCHEMBL429494 1.00 TDP1 (0.53) TDP1CA1CA2CA7CA9
SCHEMBL133184 0.98 TDP1 (0.55) TDP1CA1CA2CA7CA9
SCHEMBL29757301 0.90 TDP1 (0.56) TDP1CA1CA2CA7CA9
SCHEMBL437165 0.87 TDP1 (0.44) TDP1CA1CA2CA7CA9
SCHEMBL439895 0.86 CA1 (0.42) TDP1CA1CA2CA7CA9
SCHEMBL3690008 0.86 CA1 (0.42) TDP1CA1CA2CA7CA9
SCHEMBL7524404 0.86 CA1 (0.42) TDP1CA1CA2CA7CA9
SCHEMBL31626283 0.86 CA1 (0.42) TDP1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS GOODYEAR TIRE & RUBBER (US) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035494-A1 METHOD FOR COLD FLOW REDUCTION OF ELASTOMERS ITGA1, HSPA1A, SHC1 TDP1 1392/4885CA1 1315/4885CA2 2428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.