Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.44 |
| ▸ | PARP1 | P09874 | 7/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681002 | 0.81 | PARP10 (0.42) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL32669326 | 0.78 | PARP10 (0.44) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL32669252 | 0.77 | NOTUM (0.32) | — | |
| SCHEMBL18304941 | 0.77 | PARP10 (0.53) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL30362890 | 0.77 | PARP10 (0.53) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL14842620 | 0.74 | ACHE (0.54) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL24681313 | 0.72 | PARP10 (0.60) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL24886285 | 0.72 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL23951998 | 0.72 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL32669251 | 0.72 | PARP10 (0.51) | PARP10PARP11PARP1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | INCYTE CORP (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | PARP10 660/4885PARP11 741/4885PARP1 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.