SCHEMBL32669562

SCHEMBL32669562

CN(Cc1ccccc1C#N)C(=O)/C(C#N)=C(\O)c1cc(O)c(O)c([N+](=O)[O-])c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.62
COMT P21964 8/20 0.62
GPR35 Q9HC97 3/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41
CYP2C9 P11712 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669959 0.92 FTO (0.65) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669669 0.90 FTO (0.61) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669782 0.89 FTO (0.48) FTOCOMTMEN1LMNAKMT2A
SCHEMBL32670015 0.89 FTO (0.58) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669544 0.89 FTO (0.62) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669983 0.88 FTO (0.67) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669973 0.87 FTO (0.62) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669717 0.86 FTO (0.63) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669862 0.85 FTO (0.60) FTOCOMTGPR35MEN1LMNA
SCHEMBL32669786 0.84 FTO (0.61) FTOCOMTGPR35MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 FTO 1/4885COMT 52/4885GPR35 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.