Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 6/20 | 0.49 |
| ▸ | COMT | P21964 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | FUT4 | P22083 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669799 | 0.90 | FTO (0.43) | FTOCOMTEGFRALDH1A1MAPT | |
| SCHEMBL32669791 | 0.86 | FTO (0.40) | FTOCOMTEGFRSLC22A12 | |
| SCHEMBL32669494 | 0.85 | FTO (0.67) | FTOCOMTEGFRALDH1A1LMNA | |
| SCHEMBL32669777 | 0.83 | SLC22A12 (0.43) | FTOCOMTALDH1A1MAPTHPGD | |
| SCHEMBL32670091 | 0.80 | FTO (0.46) | FTOCOMTEGFRALDH1A1MAPT | |
| SCHEMBL32670025 | 0.79 | FTO (0.77) | FTOCOMTLMNAPTGS2CYP2C9 | |
| SCHEMBL32669541 | 0.78 | TTR (0.44) | FTOCOMTEGFRHPGD | |
| SCHEMBL32669684 | 0.78 | FTO (0.47) | FTOCOMTEGFRALDH1A1MAPT | |
| SCHEMBL32670118 | 0.76 | FTO (0.60) | FTOCOMTEGFRALDH1A1LMNA | |
| SCHEMBL32669637 | 0.76 | FTO (0.65) | FTOCOMTEGFRLMNASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | FTO 1/4885COMT 52/4885EGFR 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.