Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.57 |
| ▸ | COMT | P21964 | 6/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669835 | 0.91 | FTO (0.63) | FTOCOMTMAOAMAOB | |
| SCHEMBL32669581 | 0.91 | FTO (0.60) | FTOCOMTMAOAMAOB | |
| SCHEMBL32670142 | 0.90 | FTO (0.51) | FTOCOMTCYP2A6 | |
| SCHEMBL32669689 | 0.86 | FTO (0.57) | FTOCOMTMAOAMAOB | |
| SCHEMBL32669704 | 0.85 | FTO (0.60) | FTOCOMTMAOAMAOB | |
| SCHEMBL32670140 | 0.85 | FTO (0.60) | FTOCOMT | |
| SCHEMBL32670128 | 0.84 | FTO (0.61) | FTOCOMT | |
| SCHEMBL32670040 | 0.84 | FTO (0.56) | FTOCOMTMAOAMAOB | |
| SCHEMBL32669862 | 0.83 | FTO (0.60) | FTOCOMTMAOAMAOB | |
| SCHEMBL32669506 | 0.83 | FTO (0.69) | FTOCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | FTO 1/4885COMT 52/4885CYP2A6 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.