SCHEMBL32669725

SCHEMBL32669725

CC(C#CCN(C)C(=O)/C(C#N)=C(\O)c1cc(O)c(O)c([N+](=O)[O-])c1)CO

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.62
COMT P21964 7/20 0.62
MEN1 O00255 1/20 0.39
ABCC3 O15438 1/20 0.39
ABCC4 O15439 1/20 0.39
ABCB11 O95342 1/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
KMT2A Q03164 1/20 0.39
GPR35 Q9HC97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670155 0.89 FTO (0.48) FTOCOMTMEN1KMT2A
SCHEMBL32669605 0.88 FTO (0.61) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669506 0.86 FTO (0.69) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32670117 0.86 FTO (0.61) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669618 0.86 FTO (0.63) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669821 0.85 FTO (0.67) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32670043 0.85 FTO (0.72) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669856 0.83 FTO (0.70) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669553 0.83 FTO (0.70) FTOCOMTMEN1ABCC3ABCC4
SCHEMBL32669736 0.82 FTO (0.81) FTOCOMTMEN1ABCC3ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 FTO 1/4885COMT 52/4885MEN1 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.