Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.59 |
| ▸ | COMT | P21964 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740958 | 0.92 | FTO (0.62) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL32670106 | 0.90 | FTO (0.49) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL32669944 | 0.86 | FTO (0.53) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL32669537 | 0.85 | FTO (0.67) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL32669752 | 0.84 | FTO (0.64) | FTOCOMTKMT2ALMNAMEN1 | |
| SCHEMBL32669927 | 0.84 | FTO (0.51) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL32670109 | 0.83 | FTO (0.50) | FTOCOMTALDH1A1KMT2ALMNA | |
| SCHEMBL30740930 | 0.83 | FTO (0.72) | FTOCOMTKMT2ALMNAMEN1 | |
| SCHEMBL32669589 | 0.83 | FTO (0.64) | FTOCOMTKMT2ALMNAMEN1 | |
| SCHEMBL32669886 | 0.82 | GAA (0.41) | ALDH1A1KMT2ALMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | FTO 1/4885COMT 52/4885ALDH1A1 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.