SCHEMBL32669784

SCHEMBL32669784

COc1cc(/C(O)=C(\C#N)C(=O)N(C)Cc2cc(Br)ccc2F)cc([N+](=O)[O-])c1O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 7/20 0.49
COMT P21964 5/20 0.49
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43
ABCB1 P08183 1/20 0.42
ABCC1 P33527 1/20 0.42
TTR P02766 1/20 0.41
EGFR P00533 2/20 0.39
POLB P06746 1/20 0.38
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32669738 0.92 FTO (0.52) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669722 0.91 FTO (0.50) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669890 0.91 FTO (0.50) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32670054 0.91 FTO (0.50) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32670154 0.90 FTO (0.49) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669909 0.90 FTO (0.49) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669992 0.90 FTO (0.51) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669642 0.90 FTO (0.52) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669903 0.89 FTO (0.49) FTOCOMTALDH1A1MAPTMEN1
SCHEMBL32669739 0.89 FTO (0.48) FTOCOMTABCB1ABCC1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 FTO 1/4885COMT 52/4885ALDH1A1 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.