Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669695 | 0.94 | COMT (0.35) | COMTFTOS1PR3USP30 | |
| SCHEMBL32669510 | 0.89 | FTO (0.49) | COMTFTO | |
| SCHEMBL32669572 | 0.87 | COMT (0.40) | COMTFTOS1PR3USP30ANO1 | |
| SCHEMBL32669847 | 0.85 | COMT (0.39) | COMTFTOS1PR3USP30 | |
| SCHEMBL32669498 | 0.84 | COMT (0.39) | COMTFTOS1PR3USP30 | |
| SCHEMBL32669888 | 0.84 | FTO (0.40) | COMTFTOS1PR3ANO1 | |
| SCHEMBL32670037 | 0.83 | COMT (0.39) | COMTFTOS1PR3ANO1 | |
| SCHEMBL32669805 | 0.82 | S1PR3 (0.42) | COMTFTOS1PR3 | |
| SCHEMBL32669701 | 0.82 | FTO (0.62) | COMTFTO | |
| SCHEMBL32669936 | 0.80 | S1PR3 (0.38) | COMTFTOS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | COMT 52/4885FTO 1/4885S1PR3 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.