Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.52 |
| ▸ | COMT | P21964 | 5/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669992 | 0.90 | FTO (0.51) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32670132 | 0.89 | FTO (0.48) | FTOCOMTTTREGFRABCB1 | |
| SCHEMBL32669738 | 0.88 | FTO (0.52) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32669744 | 0.87 | FTO (0.52) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32669884 | 0.87 | FTO (0.49) | FTOCOMTTTREGFRGAA | |
| SCHEMBL32669642 | 0.87 | FTO (0.52) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32669575 | 0.86 | FTO (0.47) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32669890 | 0.86 | FTO (0.50) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32670054 | 0.86 | FTO (0.50) | FTOCOMTTTREGFRMAPT | |
| SCHEMBL32669722 | 0.86 | FTO (0.50) | FTOCOMTTTREGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | RPXDS CO LTD (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035341-A1 | FTO INHIBITORS | FTO, LDLR, GPR119 | FTO 1/4885COMT 52/4885TTR 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.