SCHEMBL32675775

SCHEMBL32675775

CCCCc1nc2c(N)nnc(N3CCCC3)c2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 5/20 0.41
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
KDM4E B2RXH2 1/20 0.38
PDE3B Q13370 7/20 0.35
PDE3A Q14432 7/20 0.35
PDE4A P27815 2/20 0.35
PDE4B Q07343 2/20 0.35
PDE4C Q08493 2/20 0.35
PDE4D Q08499 2/20 0.35
ALDH1A1 P00352 2/20 0.32
HIF1A Q16665 1/20 0.32
MAPK1 P28482 1/20 0.32
TLR7 Q9NYK1 2/20 0.31
PDE5A O76074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30663228 0.73 PI4KA (0.39) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL29840791 0.72 TLR7 (0.37) NPY5RPDE3BPDE3APDE4APDE4B
SCHEMBL30663229 0.71 PI4KA (0.40) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL29109863 0.71 PI4KA (0.40) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL32675794 0.70 PI4KA (0.39) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL29840892 0.70 TLR8 (0.41) PI4KAPI4K2BPI4K2API4KBALDH1A1
Hydrochloric Acid SCHEMBL29840678 0.69 TLR8 (0.40) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL32675782 0.69 PI4KA (0.39) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL16486305 0.69 PI4KA (0.46) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL32675790 0.68 PI4KA (0.36) PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288438-B1 DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-02-18 EP claimed