Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952406 | 0.77 | HDAC1 (0.30) | — | |
| SCHEMBL19625345 | 0.71 | SMN1; SMN2 (0.64) | ALDH1A1LMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16573711 | 0.70 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL2608434 | 0.70 | ALDH1A1 (0.61) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL13869061 | 0.70 | ALDH1A1 (0.61) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL23401799 | 0.68 | ALDH1A1 (0.64) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL12859421 | 0.68 | ALDH1A1 (0.59) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL21466344 | 0.66 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL12859423 | 0.66 | PTGS1 (0.59) | ALDH1A1CNR1CNR2GRNSORT1 | |
| SCHEMBL4083414 | 0.65 | ALDH1A1 (1.00) | ALDH1A1CNR1CNR2GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049077-A1 | Neurotrophic Receptor Tyrosine Kinase (NTRK) Inhibitors and Methods Using Same | BAYLOR COLLEGE MEDICINE (US) | 2026-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049077-A1 | Neurotrophic Receptor Tyrosine Kinase (NTRK) Inhibitors and Methods Using Same | NTRK2, NTRK3, NTRK1 | ALDH1A1 1732/4885CNR1 37/4885CNR2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.