SCHEMBL32677956

SCHEMBL32677956

COC(=O)c1cccc(N2CCC(CO)CC2)n1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 2/20 0.57
▸ HSD11B1 P28845 6/20 0.54
▸ OGA O60502 1/20 0.48
▸ CRBN Q96SW2 1/20 0.48
▸ PRKCQ Q04759 2/20 0.47
▸ TTR P02766 1/20 0.46
▸ CETP P11597 1/20 0.46
▸ PDE10A Q9Y233 1/20 0.44
▸ IRAK4 Q9NWZ3 1/20 0.42
▸ DGAT2 Q96PD7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32677959 1.00 HRH3 (0.57) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL13059653 0.89 PRKCQ (0.59) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL31753390 0.86 HSD11B1 (0.49) HRH3HSD11B1PRKCQTTRPDE10A
SCHEMBL30790724 0.84 HSD11B1 (0.55) HSD11B1PRKCQTTRPDE10AIRAK4
Hydrochloric Acid SCHEMBL3281505 0.83 HRH3 (0.58) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL14879861 0.82 HRH3 (0.58) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL20548134 0.81 HSD11B1 (0.59) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL24882086 0.81 MEN1 (0.48) —
SCHEMBL3173613 0.80 OGA (0.56) HRH3HSD11B1OGACRBNPRKCQ
SCHEMBL22849533 0.79 IRAK4 (0.53) HRH3HSD11B1OGACRBNIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055108-A1 TRIAZINE COMPOUNDS AND USES THEREOF HUTCHMED LTD (CN) 2026-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055108-A1 TRIAZINE COMPOUNDS AND USES THEREOF CBR1, CNR1, CBR3 HRH3 474/4885HSD11B1 55/4885OGA 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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