Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677959 | 0.84 | HRH3 (0.57) | HSD11B1PRKCQPDE10ATTRIRAK4 | |
| SCHEMBL32677956 | 0.84 | HRH3 (0.57) | HSD11B1PRKCQPDE10ATTRIRAK4 | |
| SCHEMBL31753390 | 0.81 | HSD11B1 (0.49) | HSD11B1PRKCQPDE10ATTR | |
| SCHEMBL30349708 | 0.80 | LMNA (0.43) | MEN1KMT2A | |
| SCHEMBL30790759 | 0.80 | PRKCQ (0.47) | HSD11B1PRKCQTTRPRKCAPRKCD | |
| SCHEMBL10002521 | 0.80 | HSD11B1 (0.58) | HSD11B1PRKCQPRKCAPRKCDIRAK4 | |
| SCHEMBL30829270 | 0.79 | PRKCQ (0.62) | HSD11B1PRKCQPRKCAPRKCDIRAK4 | |
| SCHEMBL21493103 | 0.79 | PRKCQ (0.62) | HSD11B1PRKCQPRKCAPRKCDIRAK4 | |
| SCHEMBL18391943 | 0.78 | PRKCQ (0.49) | HSD11B1PRKCQPDE10ATTRIRAK4 | |
| SCHEMBL21209434 | 0.78 | IRAK4 (0.50) | HSD11B1PRKCQPDE10AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LTD (CN) | 2026-02-26 | — | — | US | disclosed |
| EP-4581032-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024046457-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | CBR1, CNR1, CBR3 | HSD11B1 55/4885PRKCQ 4061/4885PDE10A 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.