SCHEMBL32678271

SCHEMBL32678271

COc1ccc2[nH]cc(CCNC(=O)c3ccnc(-c4ccc5[nH]cc(-c6ccccc6)c5c4)c3)c2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 7/20 0.70
KMT2A Q03164 5/20 0.61
POLB P06746 1/20 0.61
FAAH O00519 2/20 0.60
ACHE P22303 1/20 0.57
CDK4 P11802 2/20 0.56
CCND1 P24385 2/20 0.56
PTGS1 P23219 1/20 0.56
PTGS2 P35354 1/20 0.56
MEN1 O00255 4/20 0.55
MTNR1A P48039 2/20 0.55
SNCA P37840 1/20 0.54
NAMPT P43490 1/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP1A1 P04798 1/20 0.54
MPO P05164 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
HTR1A P08908 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678273 1.00 TRPV1 (0.70) TRPV1KMT2APOLBFAAHACHE
SCHEMBL32678299 0.95 TRPV1 (0.63) TRPV1KMT2APOLBFAAHACHE
SCHEMBL32678295 0.95 TRPV1 (0.63) TRPV1KMT2APOLBFAAHACHE
SCHEMBL32678333 0.93 KMT2A (0.60) TRPV1KMT2APOLBACHEMEN1
SCHEMBL32678218 0.90 LTA4H (0.63) TRPV1POLBACHECDK4CCND1
SCHEMBL32678215 0.90 LTA4H (0.63) TRPV1POLBACHECDK4CCND1
SCHEMBL32678293 0.89 CDK4 (0.67) KMT2ACDK4CCND1MEN1NAMPT
SCHEMBL32678348 0.88 CDK4 (0.56) TRPV1KMT2AFAAHACHECDK4
SCHEMBL32678349 0.88 CDK4 (0.56) TRPV1KMT2AFAAHACHECDK4
SCHEMBL32678195 0.87 SNCA (0.58) TRPV1CDK4CCND1MTNR1ASNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO claimed
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO disclosed