SCHEMBL32678331

SCHEMBL32678331

CC1(C)OB(c2ccc3[nH]cc(-c4ccc(F)cc4)c3c2)OC1(C)C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.56
LIPG Q9Y5X9 6/20 0.56
NR4A2 P43354 1/20 0.48
TDO2 P48775 8/20 0.40
IDO1 P14902 1/20 0.40
PIM1 P11309 2/20 0.39
PIM3 Q86V86 2/20 0.39
PIM2 Q9P1W9 2/20 0.39
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
IGF1R P08069 1/20 0.36
PDGFRB P09619 1/20 0.36
KIT P10721 1/20 0.36
PDGFRA P16234 1/20 0.36
FLT1 P17948 1/20 0.36
FLT4 P35916 1/20 0.36
KDR P35968 1/20 0.36
TEK Q02763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678332 1.00 LPL (0.56) LPLLIPGNR4A2TDO2IDO1
SCHEMBL15617180 0.87 LIPG (0.53) LPLLIPGNR4A2PIM1PIM3
SCHEMBL1337551 0.76 ATM (0.41) LPLLIPGTDO2IDO1
SCHEMBL20904948 0.76 LIPG (0.68) LPLLIPGTDO2IDO1PDGFRB
SCHEMBL9268634 0.75 NR4A2 (0.68) NR4A2TDO2IDO1
SCHEMBL792244 0.74 LIPG (1.00) LPLLIPG
SCHEMBL2361461 0.73 NR4A2 (0.60) NR4A2TDO2PIM1PIM3PIM2
SCHEMBL22438423 0.73 LPL (0.38) LPLLIPGTHRATHRB
SCHEMBL1337645 0.73 LPL (0.42) LPLLIPG
SCHEMBL31468044 0.72 LPL (0.45) LPLLIPGTDO2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264058-A9 NOVEL COMPOUND AND USE THEREOF 주식회사 진큐어 2026-02-26 WO disclosed