SCHEMBL32678680

SCHEMBL32678680

COCCCNc1ccnc(Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 1/20 0.50
CYP1A2 P05177 5/20 0.47
CYP2C19 P33261 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 1/20 0.47
HIF1A Q16665 1/20 0.47
TLR8 Q9NR97 1/20 0.45
HRH3 Q9Y5N1 2/20 0.44
CYP3A4 P08684 2/20 0.44
GLA P06280 1/20 0.43
CYP2C9 P11712 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
CYP2D6 P10635 1/20 0.42
NUDT1 P36639 1/20 0.42
EIF2AK2 P19525 2/20 0.41
KCNH3 Q9ULD8 1/20 0.41
HRH4 Q9H3N8 1/20 0.41
CCNT1 O60563 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32678687 1.00 HSD17B10 (0.50) HSD17B10SMN1; SMN2HTTCYP1A2CYP2C19
SCHEMBL2220720 0.90 CYP1A2 (0.56) HSD17B10SMN1; SMN2HTTCYP1A2CYP2C19
SCHEMBL14619916 0.82 TLR8 (0.66) TLR8HRH3NUDT1HRH4STK17A
SCHEMBL18072503 0.81 TLR8 (0.69) HSD17B10CYP1A2CYP2C19ALDH1A1ALOX15
SCHEMBL596209 0.81 TLR8 (0.59) TLR8HRH3NUDT1KCNH3HRH4
SCHEMBL11278962 0.79 DNM2 (0.58) TLR8HRH3NUDT1HRH4STK17A
SCHEMBL14907960 0.79 HRH3 (0.68) TLR8HRH3NUDT1HRH4STK17A
SCHEMBL11286031 0.79 NUDT1 (0.66) HTTTLR8HRH3NUDT1HRH4
SCHEMBL16139312 0.78 TLR8 (0.51) TLR8HRH3NUDT1HRH4STK17A
SCHEMBL12330669 0.78 HRH3 (0.55) CYP2C19TLR8HRH3NUDT1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041663-A1 P2X7 RECEPTOR ANTAGONISTS BREYE THERAPEUTICS APS (DK) 2026-02-26 WO disclosed