Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430160 | 1.00 | REN (0.49) | REN | |
| SCHEMBL3268786 | 0.98 | REN (0.47) | REN | |
| SCHEMBL13161215 | 0.98 | REN (0.47) | REN | |
| SCHEMBL8236338 | 0.98 | REN (0.51) | REN | |
| SCHEMBL3905443 | 0.98 | REN (0.51) | REN | |
| SCHEMBL1035501 | 0.96 | REN (0.49) | REN | |
| SCHEMBL1036511 | 0.96 | REN (0.49) | REN | |
| SCHEMBL8234666 | 0.96 | REN (0.49) | REN | |
| SCHEMBL3268169 | 0.96 | REN (0.45) | REN | |
| SCHEMBL13161201 | 0.96 | REN (0.45) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799779-B2 | Substituted piperidines as renin inhibitors | NOVARTIS AG (CH) | 2010-09-21 | — | — | US | disclosed |
| EP-1863802-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2010-06-16 | — | — | EP | disclosed |
| EP-1987834-A2 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2008-11-05 | — | — | EP | disclosed |