SCHEMBL8236338

SCHEMBL8236338

COCCCOc1ccc(C2[C@H](O)CNC[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 18/20 0.51
GRM5 P41594 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3905443 1.00 REN (0.51) RENGRM5
SCHEMBL8234666 0.98 REN (0.49) RENGRM5
SCHEMBL1036511 0.98 REN (0.49) RENGRM5
SCHEMBL1035501 0.98 REN (0.49) RENGRM5
SCHEMBL4540714 0.98 REN (0.49) RENGRM5
SCHEMBL8430160 0.98 REN (0.49) REN
SCHEMBL3267898 0.98 REN (0.49) REN
SCHEMBL13161215 0.95 REN (0.47) RENGRM5
SCHEMBL3268786 0.95 REN (0.47) RENGRM5
SCHEMBL3941670 0.94 REN (0.44) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007082907-A1 SUBSTITUTED 4-PHENYLPIPERIDINES SPEEDEL EXPERIMENTA AG (CH) 2007-07-26 WO disclosed