SCHEMBL32679271

SCHEMBL32679271

COc1ccc(S(=O)(=O)C(F)F)cc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.51
APEX1 P27695 1/20 0.51
TSHR P16473 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
GAA P10253 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
S1PR3 Q99500 1/20 0.43
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
PLA2G2A P14555 1/20 0.42
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545717 0.86 MAPK1 (0.52) MAPK1APEX1TSHRKDM4EALDH1A1
SCHEMBL987275 0.81 LMNA (0.60) MAPK1APEX1TSHRSMN1; SMN2KDM4E
SCHEMBL31079411 0.80 MAPK1 (0.54) MAPK1APEX1TSHRKDM4EALDH1A1
SCHEMBL131628 0.80 GAA (0.65) MAPK1APEX1TSHRGAALCK
SCHEMBL1364551 0.80 MAPK1 (0.54) MAPK1APEX1TSHRKDM4EALDH1A1
Hydrochloric Acid SCHEMBL9360725 0.78 MAPK1 (0.53) MAPK1APEX1TSHRKDM4EALDH1A1
Hydrochloric Acid SCHEMBL10988216 0.78 GAA (0.63) MAPK1APEX1TSHRGAALCK
SCHEMBL8544664 0.78 MAPK1 (0.56) MAPK1APEX1TSHRKDM4EALDH1A1
SCHEMBL13483626 0.78 EPAS1 (0.57) MAPK1TSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL3878089 0.77 MAPK1 (0.62) MAPK1APEX1TSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574078-A Synthesis method of 3- (difluoromethyl sulfonyl) benzoic acid compound 天津楷特药业有限公司 2026-02-27 CN disclosed