Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299184 | 0.87 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL12301960 | 0.87 | LMNA (0.76) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL1424830 | 0.86 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL21034625 | 0.85 | KMT2A (0.72) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL363917 | 0.81 | CARM1 (0.69) | KMT2AMEN1ALDH1A1POLBCARM1 | |
| Hydrochloric Acid SCHEMBL18704553 | 0.80 | CARM1 (0.68) | KMT2AMEN1ALDH1A1POLBCARM1 | |
| SCHEMBL28397981 | 0.80 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL14590545 | 0.79 | NPSR1 (0.67) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL124395 | 0.79 | NPC1 (0.79) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL2230140 | 0.79 | NPC1 (0.79) | KMT2AMEN1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120647626-B | 4-Aminopyrimidine compound targeting EGFR and AXL targets as well as preparation method and application thereof | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | 2026-02-27 | — | — | CN | disclosed |