SCHEMBL32680073

SCHEMBL32680073

CCn1c(NN)nc2ccccc2c1=O

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.72
POLB P06746 1/20 0.72
KDM4E B2RXH2 6/20 0.67
MAPT P10636 5/20 0.67
ALDH1A1 P00352 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.62
GAA P10253 2/20 0.62
MAPK1 P28482 1/20 0.56
USP2 O75604 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 2/20 0.50
PDE4B Q07343 1/20 0.50
PDE7A Q13946 1/20 0.50
GFER P55789 1/20 0.49
ADK P55263 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10921869 1.00 RAB9A (0.72) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL10916324 0.88 KDM4E (0.71) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL10917199 0.86 KDM4E (0.76) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL29446457 0.84 POLB (0.75) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL10920778 0.84 POLB (1.00) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL10916592 0.81 RAB9A (0.67) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL6282118 0.78 MAPT (0.63) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL23601086 0.78 KDM4E (0.61) RAB9APOLBKDM4EMAPTALDH1A1
SCHEMBL8347824 0.78 MEN1 (0.68) RAB9AKDM4EMAPTALDH1A1SMN1; SMN2
SCHEMBL5928741 0.78 KDM4E (0.65) RAB9APOLBKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564547-B2 Compositions, formulations, and methods for skin treatment ODDITY LABS, LLC (US) 2026-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564547-B2 Compositions, formulations, and methods for skin treatment MCOLN1, H1-0, APOL1 RAB9A 3702/4885POLB 4098/4885KDM4E 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.