Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197036 | 0.78 | PSMB5 (0.50) | NPC1RAB9APSMB5CBFBMETAP2 | |
| SCHEMBL125119 | 0.77 | CBFB (0.49) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL124418 | 0.74 | CBFB (0.54) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL32680229 | 0.74 | CBFB (0.47) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL19228827 | 0.74 | CXCR3 (0.45) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL32680204 | 0.74 | NPC1 (0.42) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL19228817 | 0.72 | RUNX1 (0.57) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL19228812 | 0.72 | RUNX1 (0.56) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL20992580 | 0.71 | CBFB (0.56) | NPC1RAB9APKMCBFBMETAP2 | |
| SCHEMBL19228819 | 0.70 | CBFB (0.46) | NPC1RAB9APKMCBFBMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702017-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2026-03-04 | — | — | EP | disclosed |