Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32680191 | 0.81 | OPRK1 (0.42) | HSD17B10GAAKDM4EWDR5ALDH1A1 | |
| SCHEMBL31486145 | 0.71 | KDM4E (0.44) | HSD17B10GAAKDM4EALDH1A1HPGD | |
| SCHEMBL10680583 | 0.69 | HSD17B10 (0.46) | HSD17B10GAAKDM4EALDH1A1HCAR3 | |
| SCHEMBL24600440 | 0.69 | RXFP1 (0.40) | HSD17B10GAAKDM4EWDR5ALDH1A1 | |
| SCHEMBL926212 | 0.69 | HSD17B10 (0.43) | HSD17B10GAAKDM4EWDR5ALDH1A1 | |
| SCHEMBL1812388 | 0.68 | KDM4E (0.43) | HSD17B10GAAKDM4EALDH1A1HPGD | |
| SCHEMBL15051643 | 0.68 | NOTUM (0.40) | — | |
| SCHEMBL1529508 | 0.66 | TDP1 (0.45) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21465765 | 0.66 | MCL1 (0.37) | KDM4EALDH1A1AKR1C3AKR1C2MCL1 | |
| SCHEMBL14718456 | 0.66 | BMPR1B (0.38) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702017-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2026-03-04 | — | — | EP | disclosed |