⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27970230 | 0.98 | SLC6A12 (0.35) | — | |
| SCHEMBL6361644 | 0.81 | — | — | |
| SCHEMBL1487372 | 0.72 | — | — | |
| SCHEMBL3364714 | 0.72 | — | — | |
| SCHEMBL1260258 | 0.72 | — | — | |
| SCHEMBL11721200 | 0.71 | — | — | |
| SCHEMBL9284283 | 0.69 | — | — | |
| SCHEMBL10750833 | 0.68 | — | — | |
| SCHEMBL7307252 | 0.68 | — | — | |
| SCHEMBL27684554 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101720319-A | Thiazolidine derivatives and methods for the preparation thereof | KAINOS MEDICINE INC | 2010-06-02 | — | — | CN | claimed |
| EP-1313471-B1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | UCB SA (BE) | 2007-04-11 | — | — | EP | claimed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | claimed |
| JP-61204189-A | — | — | None | — | — | JP | disclosed |
| WO-2025085026-A1 | SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING | T.C. ERCIYES UNIVERSITESI (TR) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085030-A1 | SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING | ERCIYES UNIVERSITESI (TR) | 2025-04-24 | — | — | WO | disclosed |
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | Frequency Therapeutics, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200316089-A1 | 1,2-DIHYDRO-3H-PYRAZOL-3-ONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. | 2020-10-08 | — | — | US | disclosed |
| US-10695723-B2 | Dye sensitized photoactive surfaces | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190352313-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2019-11-21 | — | — | US | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| WO-2000050391-A1 | NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF | MERCK & CO., INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| JP-S61204189-A | PRODUCTION OF NOVEL COMPOUND HAVING PENAM RING | CHUGAI PHARMACEUT CO LTD | 1986-09-10 | — | — | JP | disclosed |
| US-4208526-A | Process for the preparation of thiazolidin-4-one-acetic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4041166-A | Method of producing diuresis using thiazolidinone acetic acid derivatives | WARNER-LAMBERT COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-4039671-A | METHOD FOR PRODUCING DIURESIS BY ADMINISTERING CERTAIN THIAZOLIDINONE ACETIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
| US-4012395-A | FROM THEIR ESTERS IN AN ORGANIC ACID SOLUTION OF HYDROGEN BROMIDE | WARNER-LAMBERT COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4001417-A | METHOD FOR PRODUCING DIURESIS IN A MAMMAL BY USE OF THIAZOLIDINONE ACETIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3971794-A | DIURETIC | WARNER-LAMBERT COMPANY (US) | 1976-07-27 | — | — | US | disclosed |