SCHEMBL32680681

SCHEMBL32680681

O=C(NCc1cc2cnccc2n1S(=O)(=O)c1ccccc1)c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.47
KMT2A Q03164 2/20 0.45
NTRK1 P04629 1/20 0.44
PTGS2 P35354 1/20 0.43
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42
NAMPT P43490 5/20 0.42
IDE P14735 1/20 0.41
TSHR P16473 1/20 0.41
RECQL P46063 1/20 0.41
GRM4 Q14833 1/20 0.41
MTNR1B P49286 1/20 0.40
PIK3C3 Q8NEB9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558522 0.84 MTNR1B (0.45) ALDH1A1LMNAMAPTNTRK1PPARG
SCHEMBL31750757 0.80 PPARG (0.42) ALDH1A1LMNAMAPTNTRK1PPARG
SCHEMBL30765549 0.76 PPARG (0.44) ALDH1A1LMNAMAPTKMT2APPARG
SCHEMBL10552139 0.76 PIK3C3 (0.48) ALDH1A1LMNAMAPTPPARGPPARD
SCHEMBL27113334 0.76 PPARG (0.44) ALDH1A1LMNAMAPTKMT2APPARG
SCHEMBL27152696 0.76 HTR2C (0.41) ALDH1A1KMT2AIDE
SCHEMBL27144119 0.75 GAA (0.45) ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL31558473 0.75 PPARG (0.43) ALDH1A1LMNAMAPTKMT2APPARG
Hydrochloric Acid SCHEMBL27153852 0.75 PPARG (0.43) ALDH1A1LMNAMAPTKMT2APPARG
SCHEMBL30765718 0.74 NTRK1 (0.45) KMT2ANTRK1PPARGPPARAIDE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S ALDH1A1 3835/4885LMNA 345/4885MAPT 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.