SCHEMBL32683802

SCHEMBL32683802

CCOC(=O)CC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSS P25774 7/20 0.59
CTSK P43235 6/20 0.59
ACE P12821 1/20 0.49
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
SCN9A Q15858 2/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
TSHR P16473 1/20 0.43
PABPC1 P11940 1/20 0.42
REN P00797 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23125787 0.88 CTSS (0.47) CTSSCTSKACECYP1A2CYP2C9
SCHEMBL6876021 0.88 ACE (0.63) CTSSCTSKACECTSLCTSB
SCHEMBL17695878 0.88 ACE (0.63) CTSSCTSKACECTSLCTSB
SCHEMBL2106430 0.88 ACE (0.63) CTSSCTSKACECTSLCTSB
SCHEMBL2108340 0.84 CTSS (0.68) CTSSCTSKACESCN9ACTSL
SCHEMBL2108343 0.84 CTSS (0.68) CTSSCTSKACESCN9ACTSL
SCHEMBL479103 0.83 CTSS (0.67) CTSSCTSKACECTSLCTSB
SCHEMBL25382593 0.83 CTSS (0.67) CTSSCTSKACECTSLCTSB
SCHEMBL479104 0.83 CTSS (0.67) CTSSCTSKACECTSLCTSB
SCHEMBL479232 0.81 CTSS (0.72) CTSSCTSKACECTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R CTSS 1117/4885CTSK 1920/4885ACE 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.