SCHEMBL479232

SCHEMBL479232

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSS P25774 7/20 0.72
CTSK P43235 6/20 0.72
ACE P12821 2/20 0.62
ITGB3 P05106 1/20 0.62
ITGA2B P08514 1/20 0.62
PTPN1 P18031 2/20 0.56
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
PPARA Q07869 4/20 0.54
PPARG P37231 3/20 0.54
ITGA4 P13612 1/20 0.53
ITGB7 P26010 1/20 0.53
ALDH1A1 P00352 1/20 0.53
PPARD Q03181 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL479234 1.00 CTSS (0.72) CTSSCTSKACEITGB3ITGA2B
SCHEMBL2109180 1.00 CTSS (0.72) CTSSCTSKACEITGB3ITGA2B
SCHEMBL3728110 0.96 CTSS (0.67) CTSSCTSKACEITGB3ITGA2B
SCHEMBL3728107 0.96 CTSS (0.67) CTSSCTSKACEITGB3ITGA2B
SCHEMBL22962027 0.92 CTSS (0.69) CTSSCTSKACEITGB3ITGA2B
SCHEMBL30687345 0.91 CTSS (0.64) CTSSCTSKACEITGB3ITGA2B
SCHEMBL20187263 0.89 CTSS (0.66) CTSSCTSKACEITGB3ITGA2B
SCHEMBL18228975 0.89 CTSS (0.66) CTSSCTSKACEITGB3ITGA2B
SCHEMBL7438061 0.89 CTSS (0.69) CTSSCTSKACEITGB3ITGA2B
SCHEMBL30138541 0.89 CTSS (0.69) CTSSCTSKACEITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 US claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO INC (US) 2026-03-12 US disclosed
EP-4702033-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2026-03-04 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
EP-3980400-B1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS UNIV EMORY (US) 2025-08-06 EP disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
US-5169833-A Analgesics G. D. SEARLE & CO. (US) 1992-12-08 US disclosed
EP-0283956-B1 FLUORINE CONTAINING ATRIAL NATRIURETIC PEPTIDES BIO-MEGA INC. (CA) 1992-11-11 EP disclosed
US-5141924-A Bronchotracheal smooth muscle relaxant HOFFMANN-LA ROCHE, INC. (US) 1992-08-25 US disclosed
US-5095004-A Hypotensives, diuretics BIO-MEGA INC. (CA) 1992-03-10 US disclosed
WO-1991008759-A1 ALKYL SUBSTITUTED CYCLIC PENICILLANIC ACID PENTAPAPTIDES G.D. SEARLE & CO. (US) 1991-06-27 WO disclosed
EP-0405242-A2 VIP-Analogs II F. HOFFMANN-LA ROCHE AG (CH) 1991-01-02 EP disclosed
EP-0283956-A2 Fluorine containing atrial natriuretic peptides BIO-MEGA INC. (CA) 1988-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH CTSS 4120/4885CTSK 4487/4885ACE 4652/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CTSS 4022/4885CTSK 4661/4885ACE 1944/4885
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 CTSS 1371/4885CTSK 1088/4885ACE 140/4885
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 CTSS 4528/4885CTSK 3728/4885ACE 4356/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 CTSS 4503/4885CTSK 4676/4885ACE 4863/4885
US-20260069602-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SCTR, SSTR1, NPY1R CTSS 1117/4885CTSK 1920/4885ACE 926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.