Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32685342 | 1.00 | PRKCQ (0.49) | PRKCQPRKCDCSNK1EPIM1PIM3 | |
| SCHEMBL32685344 | 1.00 | PRKCQ (0.49) | PRKCQPRKCDCSNK1EPIM1PIM3 | |
| SCHEMBL30146604 | 0.85 | PRKCQ (0.40) | PRKCQPRKCDCSNK1EHDAC1ACVR1 | |
| SCHEMBL4779990 | 0.82 | PRKCQ (0.53) | PRKCQPRKCDHDAC1TRPV1 | |
| SCHEMBL32685345 | 0.82 | PRKCQ (0.53) | PRKCQPRKCDHDAC1TRPV1 | |
| SCHEMBL32685368 | 0.82 | PRKCQ (0.53) | PRKCQPRKCDHDAC1TRPV1 | |
| SCHEMBL31745447 | 0.79 | PLD1 (0.60) | PRKCQPRKCDCSNK1EHDAC1ACVR1 | |
| SCHEMBL2244221 | 0.79 | PLD1 (0.60) | PRKCQPRKCDCSNK1EHDAC1ACVR1 | |
| SCHEMBL234735 | 0.79 | PLD1 (0.60) | PRKCQPRKCDCSNK1EHDAC1ACVR1 | |
| SCHEMBL709716 | 0.79 | PLD1 (0.60) | PRKCQPRKCDCSNK1EHDAC1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577226-B2 | Compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2026-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577226-B2 | Compounds for treating Huntington's disease | HTT, HYPK, GRIN2C | PRKCQ 3806/4885PRKCD 3328/4885CSNK1E 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.