Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32685342 | 0.85 | PRKCQ (0.49) | PRKCQPRKCDCSNK1EACVR1KIT | |
| SCHEMBL32685347 | 0.85 | PRKCQ (0.49) | PRKCQPRKCDCSNK1EACVR1KIT | |
| SCHEMBL32685344 | 0.85 | PRKCQ (0.49) | PRKCQPRKCDCSNK1EACVR1KIT | |
| SCHEMBL30146642 | 0.79 | PRKCQ (0.47) | PRKCQPRKCDCSNK1EACVR1KIT | |
| SCHEMBL20038332 | 0.73 | HDAC1 (0.42) | PRKCQPRKCDCSNK1EACVR1ALDH1A1 | |
| SCHEMBL30426817 | 0.73 | HDAC1 (0.45) | PRKCQPRKCDCSNK1EACVR1KIT | |
| SCHEMBL9214403 | 0.73 | BPTF (0.61) | ALDH1A1LMNA | |
| SCHEMBL31745447 | 0.71 | PLD1 (0.60) | PRKCQPRKCDCSNK1EACVR1ALDH1A1 | |
| SCHEMBL30534242 | 0.71 | ROCK2 (0.42) | PRKCQPRKCDACVR1ALDH1A1KIT | |
| SCHEMBL234735 | 0.71 | PLD1 (0.60) | PRKCQPRKCDCSNK1EACVR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179059-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-06-05 | — | — | US | disclosed |
| US-12162870-B2 | Anticancer compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-10 | — | — | US | disclosed |
| US-20230025178-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179059-A1 | ANTICANCER COMPOUNDS | BET1, BRD4, BICRA | PRKCQ 3010/4885PRKCD 3635/4885CSNK1E 1060/4885 |
| US-20230025178-A1 | ANTICANCER COMPOUNDS | BET1, BRD4, BICRA | PRKCQ 3010/4885PRKCD 3635/4885CSNK1E 1060/4885 |
| US-12162870-B2 | Anticancer compounds | BET1, BRD4, BICRA | PRKCQ 3010/4885PRKCD 3635/4885CSNK1E 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.