Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686117 | 0.81 | CES2 (0.49) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL32685937 | 0.80 | CES2 (0.44) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL32686061 | 0.78 | HPGD (0.56) | CES2HPGDALDH1A1KDM4ERAB9A | |
| SCHEMBL32686053 | 0.77 | CES2 (0.42) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL32686052 | 0.77 | CES2 (0.42) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL32686151 | 0.74 | AKT1 (0.43) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL1609283 | 0.74 | GPR35 (0.56) | CES2HPGDALDH1A1CNR1KDM4E | |
| SCHEMBL31221898 | 0.72 | GPR35 (0.47) | HPGDMKNK1MKNK2 | |
| SCHEMBL1608957 | 0.71 | CES2 (0.55) | CES2HPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL31221985 | 0.70 | BRD4 (0.37) | ALDH1A1HSD17B10GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |